Synthesis and Evaluation of 2'-Substituted Fendiline Analogues as Antileukemics
A series of novel, 2'-substituted derivatives of fendiline have been synthesised and their ability to inhibit growth of human leukaemia cells (K562) determined. Of these derivatives, the 2'-hydroxy compounds 26 and 27 had a significantly greater inhibitory effect on K562 cells than fendiline.
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Document Type: Research Article
Publication date: June 1, 2007
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