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Publisher: Bentham Science Publishers

Volume 1, Number 1, 2004

Book review

Preface
pp. i-i(1)
Author: Reitz, Allen B.

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COVER-PAGES.
pp. i-vii(7)
Author: Bentham Science Publishers

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Review article

Targeting Protein Kinases for Bone Disease: Discovery and Development of Src Inhibitors
pp. 3-27(25)
Authors: Metcalf III, Chester A.; van Schravendijk, Marie R.; Dalgarno, David C.; Sawyer, Tomi K.

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Inhibitors of Matrix Metalloproteinases: Design, Structure and Therapeutic Applications
pp. 29-75(47)
Authors: Skiles, Jerry W.; Gonnella, Nina C.; Jeng, Arco Y.

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Mechanism-based Inhibition of Metalloproteinases
pp. 77-83(7)
Authors: Kim, Dong H.; Mobashery, Shahriar

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Selective COX-2 Inhibitors and Dual Acting Anti-inflammatory Drugs: Critical Remarks
pp. 85-95(11)
Authors: Bertolini, A.; Ottani, A.; Sandrini, M.

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Protein Farnesyltransferase Inhibitors
pp. 97-128(32)
Authors: Ayral-Kaloustian, Semiramis; Salaski, Edward J.

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The Design of Competitive, Small-molecule Inhibitors of Coagulation Factor Xa
pp. 129-152(24)
Authors: Pauls, Henry W.; Ewing, William R.; Choi-Sledeski, Yong M.

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Current Therapies and Emerging Targets for the Treatment of Diabetes
pp. 165-187(23)
Authors: Wagman, Allan S.; Nuss, John M.

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Designed Enediyne Antitumor Agents
pp. 189-214(26)
Authors: Jones, G. B.; Fouad, F. S.

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The Expanding Role of NMR in Rational Drug Design
pp. 237-271(35)
Authors: Hicks, Rickey P.; Nichols, Daniel A.

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Recent Advances in PDE4 Inhibitors as Immunoregulators and Antiinflammatory Drugs
pp. 293-345(53)
Authors: Burnouf, Catherine; Devillers, Ingrid; Pruniaux, Marie-Pierre

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Serotonin Reuptake Inhibition: An Update on Current Research Strategies
pp. 347-359(13)
Authors: Spinks, D.; Spinks, G.

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Emerging β-Amyloid Therapies for the Treatment of Alzheimer's Disease
pp. 361-384(24)
Authors: Conway, Kelly A.; Baxter, Ellen W.; Felsenstein, Kevin M.; Reitz, Allen B.

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Constitutive Activity of Brain Serotonin Receptors: Inverse Agonist Activity of Antipsychotic Drugs
pp. 399-408(10)
Authors: Purohit, Anil; Herrick-Davis, Katharine; Teitler, Milt

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Non-peptide Opioid Receptor Ligands - Recent Advances. Part I - Agonists
pp. 477-500(24)
Authors: Kaczor, Agnieszka; Matosiuk, Dariusz

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Nitric Oxide Therapies in Vascular Diseases
pp. 501-512(12)
Author: Kurowska, E. M.

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Strategies to Improve Stability and Bioavailability of Peptide Drugs
pp. 513-528(16)
Authors: Adessi, Celine; Soto, Claudio

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New Anti-HIV Agents in Preclinical or Clinical Development
pp. 543-579(37)
Author: De Clercq, Erik

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DNA Minor Groove Alkylators
pp. 581-594(14)
Author: Denny, William A.

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DNA-binding of Drugs Used in Medicinal Therapies
pp. 619-645(27)
Authors: Bischoff, G.; Hoffmann, S.; Zhdanov, R.

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The Contribution of Combinatorial Chemistry to Lead Generation: An Interim Analysis
pp. 647-662(16)
Authors: Adang, Anton E.P.; Hermkens, Pedro H.H.

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New Paradigms in Drug Design and Discovery
pp. 663-681(19)
Authors: Barchi Jr., Joseph J.; Neamati, Nouri

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Addendum

Author Index to Volume 1
pp. 683-683(1)
Author: Bentham Science Publishers

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subject Index to Volume 1
pp. 685-688(4)
Author: Bentham Science Publishers

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Instructions to Authors
pp. 689-690(2)
Author: Bentham Science Publishers

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