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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 13, Number 1, 2019

Articles

Open Access Graphical Abstracts
pp. i-iv(4)

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Open Access Meet Our Editorial Board Member
pp. 1-1(1)
Author: Wu, Qing-Hua

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Preface

Open Access Preface
pp. 2-2(1)
Author: Balani, Suresh

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Review article

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Research article

Open Access Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokineics and Pharmacodynamics of Glipizide
pp. 19-24(6)
Authors: Chaudhari, Sugandha; Zambad, Shitalkumar; Ali, Mohammed

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Open Access Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines
pp. 25-36(12)
Authors: Han, Lyrialle W.; Gao, Chunying; Zhang, Yuchen; Wang, Joanne; Mao, Qingcheng

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Open Access “Branched Tail” Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip
pp. 45-52(8)
Authors: Poloznikov, Andrey A.; Nikulin, Sergey V.; Zakhariants, Arpenik A.; Khristichenko, Anna Y.; Hushpulian, Dmitry M.; Gazizov, Ildar N.; Tishkov, Vladimir I.; Gazaryan, Irina G.

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Open Access Comparison of Rat and Human Pulmonary Metabolism Using Precision-cut Lung Slices (PCLS)
pp. 53-63(11)
Authors: Yilmaz, Yildiz; Williams, Gareth; Walles, Markus; Manevski, Nenad; Krähenbühl, Stephan; Camenisch, Gian

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Open Access Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study
pp. 64-76(13)
Authors: Ramesh, Muthusamy; Bharatam, Prasad V.

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