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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 12, Number 2, 2018

Articles

Free Content Graphical Abstracts
pp. i-iv(4)

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Free Content Meet Our Editorial Board Member
pp. 83-83(1)
Author: Liu, Kexin

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Research article

Open Access New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation
pp. 84-92(9)
Authors: Gunduz, Mithat; Argikar, Upendra A.; Cirello, Amanda L.; Dumouchel, Jennifer L.

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Using LC Retention Times in Organic Structure Determination: Drug Metabolite Identification
pp. 93-100(8)
Authors: Fitch, William L.; Khojasteh, Cyrus; Aliagas, Ignacio; Johnson, Kevin

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In Vitro Drug-Drug Interaction Potential of Sulfoxide and/or Sulfone Metabolites of Albendazole, Triclabendazole , Aldicarb, Methiocarb, Montelukast and Ziprasidone
pp. 101-116(16)
Authors: Giri, Poonam; Gupta, Lakshmikant; Naidu, Sneha; Joshi, Vipul; Patel, Nirmal; Giri, Shyamkumar; Srinivas, Nuggehally R.

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Effects of Tobacco Nicotine-Derived Nitrosamine Ketone (NNK) Exposures on Brain Alcohol Metabolizing Enzyme Activities
pp. 117-124(8)
Authors: Yalcin, Emine B.; Tong, Ming; Gallucci, Gina; de la Monte, Suzanne M.

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Open Access Genistein Affects Expression of Cytochrome P450 (CYP450) Genes in Hepatocellular Carcinoma (HEPG2/C3A) Cell Line
pp. 138-144(7)
Authors: Lepri, Sandra R.; Sartori, Daniele; Semprebon, Simone C.; Baranoski, Adrivanio; Coatti, Giuliana C.; Mantovani, Mario S.

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Open Access Quantitative Proteomics Reveals Changes in Transporter Protein Abundance in Liver, Kidney and Brain of Mice by Pregnancy
pp. 145-152(8)
Authors: Liao, Michael Z.; Gao, Chunying; Bhatt, Deepak K.; Prasad, Bhagwat; Mao, Qingcheng

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Letter to the Editor

Free Content Alam K et al. (2018) Drug Metabolism Letters; 12, 24-32.
pp. 153-153(1)
Authors: Sissung, Tristan M.; Chau, Cindy; Price, Douglas K.; Figg, William D.

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