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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 11, Number 1, 2017

Articles

Free Content Graphical Abstracts
pp. i-v(5)

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Free Content Meet Our Editorial Board Member
pp. 1-1(1)
Author: Yamazaki, Hiroshi

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Free Content Preface
pp. 2-2(1)
Author: Balani, Suresh K

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Obesity and Inflammation and Altered Clopidogrel Pharmacokinetics and Pharmacodynamics
pp. 3-13(11)
Authors: Norgard, Nicholas B.; Monte, Scott V.

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Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)
pp. 21-28(8)
Authors: Takahashi, Ryan H.; Khojasteh, Cyrus; Wright, Matthew; Hop, Cornelis E.C.A.; Ma, Shuguang

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The Role of Placental Carbonyl Reducing Enzymes in Biotransformation of Bupropion and 4-methylnitrosamino-1-(3-pyridyl)-1-butanone
pp. 29-34(6)
Authors: Fokina, Valentina M.; Patrikeeva, Svetlana L.; Oncken, Cheryl; Hankins, Gary D.V.; Ahmed, Mahmoud S.; Nanovskaya, Tatiana

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Quantification of Sulfotransferases 1A1 and 1A3/4 in Tissue Fractions and Cell Lines by Multiple Reaction Monitoring Mass Spectrometry
pp. 35-47(13)
Authors: Yoshitake, Sho; McKay-Daily, Melissa; Tanaka, Masaki; Huang, Zeqi

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Inhibitory Effect of Fruit Juices on the Doxorubicin Metabolizing Activity of Carbonyl Reductase 1
pp. 48-52(5)
Authors: Miura, Takeshi; Nagai, Katsutoshi; Kaneshiro, Shingo; Taketomi, Ayako; Nakabayashi, Toshikatsu; Konishi, Hiroki; Nishinaka, Toru; Terada, Tomoyuki

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Potential Minor Haplotypes of CYP2D6 in the Japanese Population
pp. 53-59(7)
Authors: Masuda, Masatoshi; Fujiwara, Tsutomu; Matsunaga, Masayuki; Matsumaru, Takehisa

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Gender Difference of Hepatic and Intestinal CYP3A4 in CYP3AHumanized Mice Generated by a Human Chromosome-engineering Technique
pp. 60-67(8)
Authors: Kobayashi, Kaoru; Abe, Chihiro; Endo, Mika; Kazuki, Yasuhiro; Oshimura, Mitsuo; Chiba, Kan

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