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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 10, Number 4, 2016

Articles

Graphical Abstracts
pp. i-v(5)

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Meet Our Editorial Board Member
pp. 227-227(1)
Author: P. Li, Albert

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Pharmacokinetics, Metabolism and Disposition of [14C]XQ-1H After Intravenous Administration to Male Rats
pp. 228-239(12)
Authors: Qin, Yinlin; Chen, Tao; Jin, Qiu; Guo, Kai; Feng, Hao; Heller, Dennis; Gu, Zhe-ming

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Cytochrome P450 2A6 Phenotyping Using Dietary Caffeine Salivary Metabolite Ratios and Genotyping Using Blood on Storage Cards in Non-smoking Japanese Volunteers
pp. 240-243(4)
Authors: Murayama, Norie; Shimizu, Makiko; Kobayashi, Kenta; Kishimoto, Izumi; Yamazaki, Hiroshi

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Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents
pp. 244-253(10)
Authors: Uehara, Shotaro; Uno, Yasuhiro; Suzuki, Takako; Inoue, Takashi; Utoh, Masahiro; Sasaki, Erika; Yamazaki, Hiroshi

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Genipin Inhibits the Induction of Inducible Nitric Oxide Synthase Through the Inhibition of NF-ΚB Activation in Rat Hepatocytes
pp. 254-263(10)
Authors: Nakatake, Richi; Tsuda, Takumi; Matsuura, Takashi; Miki, Hirokazu; Hishikawa, Hidehiko; Matsushima, Hideyuki; Ishizaki, Morihiko; Matsui, Kosuke; Kaibori, Masaki; Nishizawa, Mikio; Okumura, Tadayoshi; Kon, Masanori

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A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays
pp. 264-269(6)
Authors: P. Putluru, Siva; K. Matta, Murali; Ahire, Deepak; Subramanian, Murali; Sinz, Michael; Mandlekar, Sandhya

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Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme
pp. 270-277(8)
Authors: Sridhar, Jayalakshmi; Liu, Jiawang; Komati, Rajesh; Schroeder, Richard; Jiang, Quan; Tram, Phan; Riley, Kevin; Foroozesh, Maryam

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Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene
pp. 278-285(8)
Authors: Tanoue, Chiaki; Sugihara, Kazumi; Tayama, Yoshitaka; Uramaru, Naoto; Watanabe, Yoko; Ohta, Shigeru; Kitamura, Shigeyuki

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Quantification of Etodolac in Human Plasma for Pharmacokinetics and Bioequivalence Studies in 27 Korean Subjects
pp. 286-294(9)
Authors: Song, Il-Dong; Kang, Ju-Seop; Kim, Hyun-Jin; Kim, Se-Mi; Zhao, Dong-Xu; Kim, Shin-Hee; Chun, Min-Young; Lee, Kyu-Hyun

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Open Access The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells
pp. 295-305(11)
Authors: Sasabe, Tetsuo; Maeda, Shinichiro; Kishida, Kenichi; Yamano, Mariko; Miwa, Yoshihiro; Sugiyama, Toshihiro

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