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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 10, Number 3, 2016

Articles

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pp. i-iv(4)

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pp. 151-151(1)
Author: Kajbaf, M.

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New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery
pp. 152-160(9)
Authors: Ogasawara, Akira; Torimoto, Nao; Tsuda, Naoki; Aohara, Fumika; Ohashi, Rikiya; Yamada, Yasuhiro; Taniguchi, Hideki

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Intracellular Retention of Three Quinuclidine Derivatives in Caco-2 Permeation Experiments: Mechanisms and Impact on Estimating Permeability and Active Efflux Ratio
pp. 161-171(11)
Authors: Jin, Hong; Kapadnis, Sudarshan; Chen, Ting; Lee, Dooyoung; McRiner, Andrew; Cook, Andrew; Burnett, Duane A.; Koenig, Gerhard; Tang, Cuyue

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Application of a “Fit for Purpose” PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide
pp. 172-179(8)
Authors: Narayanan, Rangaraj; Hoffmann, Matthew; Kumar, Gondi; Surapaneni, Sekhar

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An Investigation of Sodium Fusidate and Recombinant Cytochrome P450 Enzymes Inhibition In-Vitro
pp. 180-186(7)
Authors: Mishriky, John; Balassone, Jacqueline; Bashour, Zenah; Kaur, Simranjit; Raman, Vini; Getachew, Robel; Osman, Narin; Guidone, Daniel; Chan, Vincent; J. Little, Peter

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Inhibition of Procarcinogen Activating Enzyme CYP1A2 Activity and Free Radical Formation by Caffeic Acid and its Amide Analogues
pp. 187-194(8)
Authors: Narongchai, Paitoon; Niwatananun, Kanokporn; Narongchai, Siripun; Kusirisin, Winthana; Jaikang, Churdsak

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The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes
pp. 195-199(5)
Authors: Liu, Hong; Narayanan, Rangaraj; Hoffmann, Matthew; Surapaneni, Sekhar

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Identification and Characterization of the Human Cytosolic Sulfotransferases Mediating the Sulfation of Clioquinol and Iodoquinol
pp. 200-205(6)
Authors: Yamamoto, Akihiro; Debrah-Pinamang, Maame; J. DiModica, Nicholas; Kurogi, Katsuhisa; A. Naqvi, Ali; Hui, Ying; Sakakibara, Yoichi; Suiko, Masahito; Liu, Ming-Cheh

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UHPLC Quantitation Method for New Thiazolidinedione LPSF/GQ-02 and In Vitro/In Vivo Kinetic Studies
pp. 206-212(7)
Authors: Monalizi Vieira, Carla; Leandro de Campos, Michel; Carvalho Padilha, Elias; Pitta, Marina; da Rocha Pitta, Ivan; do Carmo Alves de Lima, Maria; Gonçalves Peccinini, Rosângela

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CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study
pp. 213-218(6)
Authors: Abdulrahman AlMeman, Ahmad; Ismail, Rusli; Perola, Markus

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