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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 9, Number 1, 2015

Articles

Free Content Graphical Abstracts:
pp. i-iii(3)

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Free Content Meet Our Editorial Board Member:
pp. 1-1(1)
Author: Gomez-Lechon, MÂȘ J.

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Free Content Preface:
pp. 2-2(1)
Author: K. Balani, Suresh

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Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays
pp. 3-7(5)
Authors: Murayama, Norie; Usui, Takashi; Slawny, Nicky; Chesne, Christophe; Yamazaki, Hiroshi

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The Effect of Protein Restriction in the In Vitro Metabolism of Albendazole in Rats
pp. 8-16(9)
Authors: Roberta A. Belaz, Katia; de O. Cardoso, Josiane; Alberto da Silva, Carlos; V. Oliveira, Regina

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A Modified Procedure for Estimating the Impact of the Uptake on the Overall Biliary Clearance in Sandwich Culture of Rat Hepatocytes
pp. 17-27(11)
Authors: Jemnitz, Katalin; Szabo, Monika; Batai-Konczos, Attila; Szabo, Pal; Magda, Balazs; Veres, Zsuzsa

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Metabolism and Disposition of Pacritinib (SB1518), an Orally Active Janus Kinase 2 Inhibitor in Preclinical Species and Humans
pp. 28-47(20)
Authors: Jayaraman, Ramesh; Pasha, Mohammed K.; Williams, Anthony; Cee Goh, Kee; Ethirajulu, Kantharaj

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In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities
pp. 48-62(15)
Authors: Awortwe, Charles; K. Manda, Vamshi; Avonto, Cristina; I. Khan, Shabana; A. Khan, Ikhlas; A. Walker, Larry; J. Bouic, Patrick; Rosenkranz, Bernd

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