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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 8, Number 2, 2014

Articles

Direct and Rapid Transcript Analysis Assay for CYP mRNA Expression and Inducibility in Human Primary Hepatocytes
pp. 77-87(11)
Authors: Mattinen, Laura; Kublbeck, Jenni; Rechardt, Oona; Honkakoski, Paavo; Rautio, Jari

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Sulfation of Phenylephrine by the Human Cytosolic Sulfotransferases
pp. 96-100(5)
Authors: Yamamoto, Akihiro; Kim, Jiwan; Liu, Ming-Yih; Kurogi, Katsuhisa; Sakakibara, Yoichi; Suiko, Masahito; Liu, Ming-Cheh

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Anaerobic Metabolism of the Agro-Pesticide Nitroxinil by Bovine Ruminal Fluid
pp. 101-108(8)
Authors: Irazoqui, Ignacio; Rodriguez, Alfonso; Birriel, Estefanía; Gabay, Martin; Lavaggi, Maria L.; Luis Repetto, Jose; Cajarville, Cecilia; Gonzalez, Mercedes; Cerecetto, Hugo

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A Systematic Evaluation of Solubility Enhancing Excipients to Enable the Generation of Permeability Data for Poorly Soluble Compounds in Caco-2 Model
pp. 109-118(10)
Authors: Shah, Devang; Paruchury, Sundeep; Matta, Muralikrishna; Chowan, Gajendra; Subramanian, Murali; Saxena, Ajay; G. Soars, Matthew; Herbst, John; Haskell, Roy; Marathe, Punit; Mandlekar, Sandhya

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Inhibition and Structural Changes of Liver Alkaline Phosphatase by Tramadol
pp. 129-134(6)
Authors: Minai-Tehrani, Dariush; Eslami, Mahya; Khazaei, Nafsa; Katebian, Elmira; Azizi, Leila; Yazdi, Fatemeh; Hosseini, Akram S.; Taheri, Mohammadreza

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The Influences of Aconitine, an Active/Toxic Alkaloid from Aconitum, on the Oral Pharmacokinetics of CYP3A Probe Drug Buspirone in Rats
pp. 135-144(10)
Authors: Zhu, Lijun; Lu, Linlin; Guo, Enshuang; Wu, Jinjun; Wang, Ying; Hu, Ming; Liu, Zhongqiu

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