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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 8, Number 1, 2014

Articles

Free Content Editorial:
pp. 1-1(1)
Author: K. Balani, Suresh

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A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs
pp. 19-30(12)
Authors: F. Moghaddam, Mehran; Tang, Yang; O’Brien, Zhihong; J. Richardson, Samantha; Bacolod, Maria; Chaturedi, Prasoon; Apuy, Julius; Kulkarni, Ashutosh

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A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening
pp. 36-42(7)
Authors: Penner, Natalia; Liu, Xiaojing; Prakash, Chandra

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Comparison of Catalytic Properties of Cytochromes P450 3A4 and 3A5 by Molecular Docking Simulation
pp. 43-50(8)
Authors: Niwa, Toshiro; Yasumura, Motohiro; Murayama, Norie; Yamazaki, Hiroshi

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Extrahepatic Metabolism may Complicate the IVIVC in Rats
pp. 51-66(16)
Author: Fonsi, Massimiliano

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