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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 7, Number 2, 2013

Articles

Oxidative Stress and Lipid Peroxidation in Prolonged Users of Methamphetamine
pp. 79-82(4)
Authors: Solhi, Hassan; Malekirad, Aliakbar; Mohammad Kazemifar, Amir; Sharifi, Farzaneh

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Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb- Drug Interactions
pp. 83-95(13)
Authors: Awortwe, Charles; J. Bouic, Patrick; M. Masimirembwa, Collen; Rosenkranz, Bernd

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Preclinical Drug Metabolism and Pharmacokinetics, and Prediction of Human Pharmacokinetics and Efficacious Dose of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237)
pp. 96-104(9)
Authors: J. Yang, Johnny; Li, Yu; Chakravarty, Arijit; Lu, Chuang; Q. Xia, Cindy; Chen, Susan; Pusalkar, Sandeep; Zhang, Mengkun; Ecsedy, Jeffrey; G. Manfredi, Mark; Wu, Jing-Tao; Chyi Shyu, Wen; K. Balani, Suresh

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A Review of Pharmacokinetic Parameters of Metabolites and Prodrugs
pp. 105-116(12)
Authors: Leandro de Campos, Michel; Carvalho Padilha, Elias; Goncalves Peccinini, Rosangela

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Culture Duration-, Donor-, and Medium-Dependent Changes in OATP1B3- Mediated Telmisartan Uptake in Human Hepatocytes
pp. 117-125(9)
Authors: Zhu, Qing; Xia, Haiyan; Q. Xia, Cindy; Yang, Qian; Doshi, Utkarsh; P. Li, Albert; Liao, Mingxiang

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Metabolite Characterization of Anti-cancer Agent Gefitinib in Human Hepatocytes
pp. 126-136(11)
Authors: Surve, Prashant; Ravindran, Selvan; Acharjee, Arghya; Rastogi, Himanshu; Basu, Sudipta; Honrao, Pradnya

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The Effect of Pomelo Mix Ethyl Acetate Extract on CYP3A6 and P-Glycoprotein Gene Transcripts in Rabbits
pp. 137-140(4)
Authors: M. Irshaid, Yacoub; A. Zihlef, Malek; M Zmeili, Suheil; T. Al-Antary, Eman; G. Zmaily, Mais; N. Al-Embideen, Somya; O. Amireh, Abdallah

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