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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 7, Number 1, 2013

Articles

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pp. 1-1(1)
Author: Prakash, Chandra

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Mechanistic Evaluation of Substrate Inhibition Kinetics Observed From Aldehyde Oxidase-Catalyzed Reactions
pp. 2-14(13)
Authors: W.J. Wang, Stephen; Abdul-Hadi, Kojo; Cohen, Lawrence; Q. Xia, Cindy

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Inhibition of Hepatobiliary Transporters by A Novel Kinase Inhibitor Contributes to Hepatotoxicity in Beagle Dogs
pp. 15-22(8)
Authors: Scott Daniels, John; Lai, Yurong; South, Sarah; Chiang, Po-Chang; Walker, Daniel; Feng, Bo; Mireles, Rouchelle; O. Whiteley, Laurence; W. Mckenzie, Jeremy; Stevens, Jeffrey; Mourey, Robert; Anderson, David; W. Davis II, John

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Biopharmaceutical Characterization, Metabolism, and Brain Penetration of the Triple Reuptake Inhibitor Amitifadine
pp. 23-33(11)
Authors: P. Bymaster, Frank; Chao, Piyun; Schulze, Heidi; V. Tran, Pierre; D. Marshall, Randall

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Sulfaphenazole and α-Naphthoflavone Attenuate the Metabolism of the Synthetic Cannabinoids JWH-018 and AM2201 Found in K2/Spice
pp. 34-38(5)
Authors: C. Chimalakonda, Krishna; P. James, Laura; Radominska-Pandya, Anna; H. Moran, Jeffery

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Effects of Obesity Induced by High-Fat Diet on the Pharmacokinetics of Atazanavir in Rats
pp. 39-46(8)
Authors: Kobuchi, Shinji; Fukushima, Keizo; Aoyama, Hiroaki; Ito, Yukako; Sugioka, Nobuyuki; Takada, Kanji

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Lepidium Sativum but not Nigella Sativa Affects Carbamazepine Disposition in an Animal Model
pp. 47-51(5)
Authors: M. Alkharfy, Khalid; I. Al-Jenoobi, Fahad; Aftab Alam, Mohd.; M. Al-Mohizea, Abdullah; A. Al-Suwayeh, Saleh; M. Korashy, Hesham; A. Khan, RaoM.; Muzaffar, Iqbal

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Capillary Zone Electrophoresis for Separation and Quantitative Determination of Mexiletine and its Main Phase I Metabolites
pp. 52-57(6)
Authors: Bruno, Claudio; Maddalena Cavalluzzi, Maria; Carocci, Alessia; Catalano, Alessia; Franchini, Carlo; Lentini, Giovanni

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Pharmacokinetics of Hydroxymethylnitrofurazone and Its Parent Drug Nitrofurazone in Rabbits
pp. 58-64(7)
Authors: Antonio Ferraz Nogueira Filho, Marco; Carvalho Padilha, Elias; Leandro de Campos, Michel; Vinicius de Pontes Machado, Diego; Gomes Davanço, Marcelo; Christina Pestana, Kelly; Man Chin, Chung; Gonçalves Peccinini, Rosângela

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Drug Metabolite Generation Using a Laboratory Evolved NADPH Independent Cytochrome P450: Application of in vitro and in silico Approaches
pp. 68-77(10)
Authors: T. L. Chigorimbo-Murefu, Nyaradzo; Njoroge, Mathew; Louw, Stefan; Mugumbate, Grace; Chibale, Kelly

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