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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 6, Number 3, 2012

Articles

Open Access Update on the Evidence of Statin Treatment to Reduce Plaque Vulnerability
pp. 151-156(6)
Authors: Montecucco, Fabrizio; Pende, Aldo

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Open Access Metabolism of R- and S-Warfarin by CYP2C19 into Four Hydroxywarfarins
pp. 157-164(8)
Authors: Kim, So-Young; Kang, Ji-Yeon; Hartman, Jessica H.; Park, Sun-Ha; Jones, Drew R.; Yun, Chul-Ho; Boysen, Gunnar; Miller, Grover P.

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Open Access Bilitranslocase is Involved in the Uptake of Bromosulfophthalein in Rat and Human Liver
pp. 165-173(9)
Authors: Terdoslavich, Michela; de Graaf, Inge A.M.; Proost, Johannes H.; Cocolo, Alessandra; Passamonti, Sabina; Groothuis, Geny M.M.

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Open Access A Simple Identification of Novel Carbonyl Reducing Enzymes in the Metabolism of the Tobacco Specific Carcinogen NNK
pp. 174-181(8)
Authors: Skarydova, Lucie; Zverinova, Michaela; Stambergova, Hana; Wsol, Vladimir

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Open Access Stereospecific Synthesis of m-Hydroxymexiletine Enantiomers
pp. 182-186(5)
Authors: Catalano, Alessia; Carocci, Alessia; Lentini, Giovanni; Defrenza, Ivana; Bruno, Claudio; Franchini, Carlo

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Open Access Evaluation of Micronuclei Induction Capacity and Mutagenicity of Organochlorine and Organophosphate Pesticides
pp. 187-197(11)
Authors: Yaduvanshi, Santosh K.; Srivastava, Nalini; Marotta, Francesco; Jain, Shalini; Yadav, Hariom

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Open Access Antimutagenic Activity of Lutein –An Oxycarotenoid Present in the Macula and its Inhibition of Cytochrome P 450 Enzymes in vitro
pp. 213-220(8)
Authors: Sindhu, Edakkadath R.; Firdous, Alikkunjhi P.; Viswanathan, Ramnath; Kuttan, Ramadasan

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