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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 6, Number 2, 2012

Articles

Open Access Cytochrome P450 2A6 Phenotyping Based on Dietary Caffeine Intake in a Japanese Population of Non-smokers
pp. 67-72(6)
Authors: Kimura, Miyuki; Shimizu, Makiko; Kiyotani, Kazuma; Nakagawa, Kazuko; Kamataki, Tetsuya; Yamazaki, Hiroshi

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Open Access In Vitro Drug Metabolism of Green Tea Catechins in Human, Monkey, Dog, Rat and Mouse Hepatocytes
pp. 73-93(21)
Authors: W. Chen, Wendy; Qin, Geng-Yao; Zhang, Ting; Feng, Wan-Yong

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Open Access Limitations of S-Warfarin Truncated Area Under the Concentration-Time Curve to Predict Cytochrome P450 2c9 Activity
pp. 94-101(8)
Authors: C. Wu, Jerry; N. Nafziger, Anne; S. Bertino, Joseph; D. Ma, Joseph

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Open Access Single-dose Pharmacokinetics and Tolerability of Oral Delta-9- Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis
pp. 102-108(7)
Authors: Joerger, Markus; Wilkins, Justin; Fagagnini, Stefania; Baldinger, Reto; Brenneisen, Rudolf; Schneider, Ursula; Goldman, Bea; Weber, Markus

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Open Access Sulfation of Buprenorphine, Pentazocine, and Naloxone by Human Cytosolic Sulfotransferases
pp. 109-115(7)
Authors: Kurogi, Katsuhisa; Chen, Mei; Lee, Yoonjung; Shi, Bo; Yan, Teng; Liu, Ming-Yih; Sakakibara, Yoichi; Suiko, Masahito; Liu, Ming-Cheh

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Open Access Caffeine Induces CYP1A2 Expression in Rat Hepatocytes but not in Human Hepatocytes
pp. 116-119(4)
Authors: Vaynshteyn, David; Jeong, Hyunyoung

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Open Access Idebenone Treatment Mediates the Effect of Menadione Oxidative Stress Damage in Saccharomyces cerevisiae
pp. 120-123(4)
Authors: Gamondi, Oliver; Chapela, Sebastian; Nievas, Ines; Burgos, Isabel; Alonso, Manuel; Stella, Carlos

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Open Access An Improved Synthesis of m-Hydroxymexiletine, a Potent Mexiletine Metabolite
pp. 124-128(5)
Authors: Catalano, Alessia; Carocci, Alessia; Lentini, Giovanni; Defrenza, Ivana; Maddalena Cavalluzzi, Maria; Franchini, Carlo

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Open Access A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier
pp. 134-144(11)
Authors: Kallem, Rajareddy; P. Kulkarni, Chetan; Patel, Dakshay; Thakur, Megha; Sinz, Michael; P. Singh, Sheelendra; Shahe Mahammad, S.; Mandlekar, Sandhya

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Open Access The Pharmacokinetics and Metabolism Study of Sodium 7,4' -oxo-acetic Acid Daidzein in Rat
pp. 145-150(6)
Authors: Wang, Shujun; Gao, Ruixue; Xu, Kun; Yi, Xiaojun; Hou, Wei; Liu, Chengyu; Cheng, Fei

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