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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 5, Number 1, 2011

Articles

Effect of Pinocembrin Isolated from Boesenbergia pandurata on Xenobiotic-Metabolizing Enzymes in Rat Liver
pp. 1-5(5)
Authors: Punvittayagul, Charatda; Wongpoomchai, Rawiwan; Taya, Sirinya; Pompimon, Wilart

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An In Vitro, High Throughput, Seven CYP Cocktail Inhibition Assay for the Evaluation of New Chemical Entities Using LC-MS/MS
pp. 17-24(8)
Authors: N. Otten, Jennifer; P. Hingorani, Gary; P. Hartley, Dylan; D. Kragerud, Scott; B. Franklin, Ronald

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Mice Brain Nitric Oxide Synthase Response Induced by Anaesthetics and Other Porphyrinogenic Drugs
pp. 25-29(5)
Authors: Lavandera, Jimena; Batlle, Alcira; Maria Buzaleh, Ana

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A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry
pp. 30-39(10)
Authors: Kajbaf, Mahmud; Longhi, Raffaele; Montanari, Dino; Vinco, Federica; Rigo, Monica; Fontana, Stefano; D. Read, Kevin

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Statin Drugs, Metabolic Pathways, and Asthma: A Therapeutic Opportunity Needing Further Research
pp. 40-44(5)
Authors: A. Zeki, Amir; J. Kenyon, Nicholas; Goldkorn, Tzipora

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The Metabolism of Methazolamide - Identification of Metabolites in Guinea Pig Urine
pp. 45-54(10)
Authors: Kishida, Kenichi; Yamamura, Norihiro; Iwai, Yoshiaki; Sakamoto, Yoshiteru; Kuhara, Makihiko; Sasabe, Tetsuo

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Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11 -Hydroxysteroid Dehydrogenase Type 1 (11 -HSD1) Inhibitors
pp. 55-63(9)
Authors: Wang, Mengmeng; Tian, Xianbin; Leung, Louis; Wang, Jianyao; Houvig, Nicole; Xiang, Jason; Saiah, Eddine; Hahm, Seung; Suri, Vipin; Xu, Xin

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