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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 4, Number 3, 2010

Articles

Evaluation of Cytochrome P450 Inhibition Assays Using Human Liver Microsomes by a Cassette Analysis /LC-MS/MS
pp. 120-128(9)
Authors: Zambon, Serenella; Fontana, Stefano; Kajbaf, Mahmud

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Induction of CYP2B6 and CYP3A4 Expression by 1-Aminobenzotriazole (ABT) in Human Hepatocytes
pp. 129-133(5)
Authors: Yang, Kyunghee; Hye Koh, Kwi; Jeong, Hyunyoung

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Schistosoma mansoni Changes the Activity of Phase II Drug-Metabolizing Enzymes: Role of Praziquantel as Antibilharzial Drug
pp. 134-138(5)
Authors: A. Sheweita, Salah; Hassan, Mostafa; A. Bahashwan, Saleh

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Free Content L-4F Differentially Alters Plasma Levels of Oxidized Fatty Acids Resulting in more Anti-Inflammatory HDL in Mice
pp. 139-148(10)
Authors: Imaizumi, Satoshi; Grijalva, Victor; Navab, Mohamad; J. Van Lenten, Brian; C. Wagner, Alan; Anantharamaiah, G.M.; M. Fogelman, Alan; T. Reddy, Srinivasa

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Pharmacokinetics, Disposition, and Metabolism of [14C]-Nebicapone in Humans
pp. 149-162(14)
Authors: C. Wright, Lyndon; Maia, Joana; I. Loureiro, Ana; Almeida, Luis; Soares-Da-Silva, Patricio

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Multiple Species Metabolism of PHA-568487, A Selective α7 Nicotinic Acetylcholine Receptor Agonist
pp. 163-172(10)
Authors: Barclay Shilliday, F.; P. Walker, Daniel; Gu, Chungang; Fang, Xiaojun; Thornburgh, Bruce; D. Fate, Gwendolyn; Scott Daniels, J.

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The Effect of Licorice Drink on the Systemic Exposure of Verapamil in Rabbits
pp. 173-179(7)
Authors: D. Al-Deeb, Ibraheem; A. Arafat, Tawfeeq; M. Irshaid, Yacoub

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Morphologic Characterization of PhoenixBio® (uPA+/+/SCID) Humanized Liver Chimeric Mouse Model
pp. 180-184(5)
Authors: A. Peterson, Richard; L. Krull, David; Roger Brown, H.; de Serres, Mark

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