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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 4, Number 2, 2010

Articles

Pharmacokinetics of Pseudoephedrine in Rats, Dogs, Monkeys and Its Pharmacokinetic-Pharmacodynamic Relationship in a Feline Model of Nasal Congestion
pp. 56-61(6)
Authors: R. Palamanda, Jairam; Mei, Hong; Morrison, Richard; L. McLeod, Robbie; McCormick, Kevin; Corboz, Michel; Xu, Xiaoying; Korfmacher, Walter; Broske, Lisa; A. Nomeir, Amin

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Sulfation of Drug Compounds by the Zebrafish Cytosolic Sulfotransferases (SULTs)
pp. 62-68(7)
Authors: Kurogi, Katsuhisa; Dillon, Jeremiah; Nasser, Ahmed; Liu, Ming-Yih; E. Williams, Frederick; Sakakibara, Yoichi; Suiko, Masahito; Liu, Ming-Cheh

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Application of Modern Drug Metabolism Structure Determination Tools and Assays to the In Vitro Metabolism of Imiloxan
pp. 77-87(11)
Authors: L. Fitch, William; Chen, Yuan; Liu, Liling; Paehler, Axel; Young, May

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Identifying a Higher Throughput Assay for Metabolism Dependent Inhibition (MDI)
pp. 104-113(10)
Authors: Kajbaf, Mahmud; Palmieri, Emiliano; Longhi, Raffaele; Fontana, Stefano

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siRNA-Mediated Knock-Down of P-Glycoprotein Expression Reveals Distinct Cellular Disposition of Anticancer Tyrosine Kinases Inhibitors
pp. 114-119(6)
Authors: Haouala, Amina; Rumpold, Holger; Untergasser, Gerold; Buclin, Thierry; Ris, Hans-Beat; Widmer, Nicolas; A. Decosterd, Laurent

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