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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 4, Number 1, 2010

Articles

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Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1
pp. 9-14(6)
Authors: Elsherbiny, Marwa E.; El-Kadi, Ayman O.S.; Brocks, Dion R.

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An Evaluation of Ondansetron Binding Interactions with Human Cytochrome P450 Enzymes CYP3A4 and CYP2D6
pp. 25-30(6)
Authors: Lewis, David F.V.; Ito, Yuko; Eddershaw, Peter J.; Dickinsd, Maurice; Goldfarb, Peter S.

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Development of a UGT1A1 Reporter Gene Assay for Induction Studies: Correlation Between Reporter Gene Data and Regulation of UGT1A1 in Human Hepatocytes
pp. 31-38(8)
Authors: Enoru-Eta, Julius; Yengi, Lilian G.; He, Xiaoyang; Kubik, Joseph; Kao, John; Scatina, Joann

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Impact of Ritonavir, Atazanavir and Their Combination on the CYP3A4 Induction by Efavirenz in Primary Human Hepatocytes
pp. 45-50(6)
Authors: Mugundu, Ganesh M.; Hariparsad, Niresh; Desai, Pankaj B.

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Effect of Black Seed on Dextromethorphan O- and N-Demethylation in Human Liver Microsomes and Healthy Human Subjects
pp. 51-55(5)
Authors: Al-Jenoobi, F. I.; Al-Thukair, A. A.; Abbas, F. A.; Ansari, M. J.; Alkharfy, K. M.; Al-Mohizea, A. M.; Al-Suwayeh, S. A.; Jamil, S.

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