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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 3, Number 3, 2009

Articles

Studies of Acetaminophen and Metabolites in Urine and Their Correlations with Toxicity Using Metabolomics
pp. 130-136(7)
Authors: Sun, Jinchun; Schnackenberg, Laura K.; Beger, Richard D.

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Effect of Albendazole Administration on Pharmacokinetic Aspects of Tylosin in Lactating Goats
pp. 137-143(7)
Authors: Atef, M.; Ramadan, A.; Darwish, A. S.; Fahim, Aisha M.M.

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Comparison of Pharmacokinetics of Cyclosporine A in Cadaveric and Living- Related Renal Transplant Recipients and in an Experimental Rat Model of Renal Failure
pp. 152-161(10)
Authors: Sugioka, Nobuyuki; Fujimoto, Katsukuni; Tanaka, Yuka; Fukushima, Keizo; Ito, Yukako; Kokuhu, Takatoshi; Okamoto, Masahiko; Yoshimura, Norio; Takada, Kanji

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Metabolism of Loratadine and Further Characterization of Its In Vitro Metabolites
pp. 162-170(9)
Authors: Ghosal, Anima; Gupta, Samir; Ramanathan, Ragu; Yuan, Yuan; Lu, Xiaowen; Su, Ai Duen (Iris); Alvarez, Narciso; Zbaida, Shmuel; Chowdhury, Swapan K.; Alton, Kevin B.

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Evaluation of CYP1A1 and CYP2B1/2 m-RNA Induction in Rat Liver Slices Using the NanoString® Technology: A Novel Tool for Drug Discovery Lead Optimization
pp. 171-175(5)
Authors: Palamanda, Jairam R.; Kumari, Pramila; Murgolo, Nicholas; Benbow, Larry; Lin, Xinjie; Nomeir, Amin A.

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Fatal Lactic Acidosis Precipitated by Nifedipine in a Patient Treated with Disulfiram and Antiretrovirals
pp. 176-180(5)
Authors: Moling, Oswald; Rimenti, Giovanni; Pristera, Raffaele; Vedovelli, Claudio; Pagani, Leonardo; Spoladore, Greta; Mian, Peter

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Revisiting the Metabolism of Ketoconazole Using Accurate Mass
pp. 191-198(8)
Authors: Fitch, William L.; Tran, Thuy; Young, May; Liu, Liling; Chen, Yuan

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Genetic Polymorphisms in UDP-Glucuronosyltransferase 1A6 Are Not Associated with NSAIDs-Related Peptic Ulcer Haemorrhage
pp. 199-204(6)
Authors: van Oijen, Martijn G.H.; Koetsier, Marjolein I.A.; Laheij, Robert J.F.; Roelofs, Hennie M.J.; te Morsche, Rene H.M.; Peters, Wilbert H.M.; Verheugt, Freek W.A.; Jansen, Jan B.M.J.; Drenth, Joost P.H.

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