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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 3, Number 2, 2009

Articles

Differences in Lopinavir Plasma Concentrations Comparing Kaletra® Film Coated Tablets and Soft Gelatine Capsules That Result in Various Lipid Abnormalities
pp. 67-69(3)
Authors: Morello, Judit; Soriano, Vincent; Blanco, Francisco; Rubio, Antonio J.; Jimenez-Nacher, Inmaculada; Rodriguez-Novoa, Sonia

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Esterase Activities in the Blood, Liver and Intestine of Several Preclinical Species and Humans
pp. 70-77(8)
Authors: Berry, Loren M.; Wollenberg, Lance; Zhao, Zhiyang

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High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points
pp. 78-82(5)
Authors: Albaugh, Daniel; Farrell, Thomas; Langan, Michael; Lai, W. G.

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Inhibition of Human Aromatase by Myosmine
pp. 83-86(4)
Authors: Doering, Irene L.; Richter, Elmar

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Electronic and Structural Aspects of P450-Mediated Drug Metabolism
pp. 87-100(14)
Authors: Lewis, David F.V.; Ito, Yuko; Lake, Brian G.

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High-Throughput Evaluation of CYP1A1 and 2B1 Induction in Rat Liver Slices Using a Semi-Automated System
pp. 108-114(7)
Authors: Palamanda, Jairam R.; Lin, Xinjie; Kumari, Pramila; Nomeir, Amin A.

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A Comparative Study on the Stability of Silybin and That in Silymarin in Buffers and Biological Fluids
pp. 115-119(5)
Authors: Tang, Ning; Wu, Danni; Lu, Yi; Chen, Jian; Zhang, Bei; Wu, Wei

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Inhibitory Properties of Trapping Agents: Glutathione, Potassium Cyanide, and Methoxylamine, Against Major Human Cytochrome P450 Isoforms
pp. 125-129(5)
Authors: Zhang, Chenghong; Wong, Susan; Delarosa, Erlie M.; Kenny, Jane R.; Halladay, Jason S.; Hop, Cornelis E.; Khojasteh-Bakht, Siamak C.

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