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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 2, Number 3, 2008

Articles

Editorial
pp. 151-152(2)
Author: Prakash, Chandra

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Microsome Biocolloids for Rapid Drug Metabolism and in hibition Assessment by LC-MS
pp. 158-162(5)
Authors: Bajrami, Besnik; Krishnan, Sadagopan; Rusling, James F.

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Effects of Cyclosporine A and Itraconazole on Permeability, Biliary Excretion and Pharmacokinetics of Amlidipine
pp. 163-168(6)
Authors: Ni, Liang; Yu, Xue; Yu, Qiaoling; Chen, Xijing; Jia, Lee

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Quantitative Relationship Between Rifampicin Exposure and Induction of CYP3a11 in SXR Humanized Mice: Extrapolation to Human CYP3A4 Induction Potential
pp. 169-175(7)
Authors: Kim, Sean; Pray, Devin; Zheng, Ming; Morgan, Danial G.; Pizzano, Jenifer G.; Zoeckler, Mary E.; Chimalakonda, Anjaneya; Sinz, Michael W.

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Aldehyde Oxidase Activity and Inhibition in Hepatocytes and Cytosolic Fraction from Mouse, Rat,Monkey and Human
pp. 176-183(8)
Authors: Sahi, Jasminder; Khan, Kishore K.; Black, Chris B.

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Troglitazone Thiol Adduct Formation in Human Liver Microsomes: Enzyme Knietics and Reaction Phenotyping
pp. 184-189(6)
Authors: Gan, Jinping; Qu, Qinling; He, Bing; Shyu, Wen C.; Rodrigues, A. D.; He, Kan

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Proposed New Addition to 3Rs for Ethical and Humane Use of Rats in Pharmacokinetic Studies - ‘Recycle’
pp. 193-197(5)
Authors: Balani, Suresh K.; Lu, Chaung; Cardoza, Kym; Berg, Cicely; Zhang, Ji; Lee, Frank W.

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Free Content Allosteric Modulation of SULT2A1 by Celecoxib and Nimesulide: Computational Analyses
pp. 198-204(7)
Authors: Yalcin, Emine B.; Struzik, Scott M.; King, Roberta S.

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Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry
pp. 205-209(5)
Authors: Lahoz, Agustin; Donato, Maria T.; Picazo, Laura; Castell, Jose V.; Gomez-Lechon, Maria Jose

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Absolute Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase (UGT) Enzyme Isoforms 1A1 and 1A6 By Tandem LC-MS
pp. 210-222(13)
Authors: Fallon, John K.; Harbourt, David E.; Maleki, Saber H.; Kessler, Fay K.; Ritter, Joseph K.; Smith, Philip C.

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Role of P-glycoprotein in the Transport of Tanshinone I, One Active Triterpenoid from Salvia miltiorrhiza
pp. 223-230(8)
Authors: Li, Xing-Xiao; Zhou, Zhi-Wei; Zhou, Shu-Feng

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