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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 2, Number 1, 2008

Articles

Visualization of First-Pass Drug Metabolism of Terfenadine by MALDIImaging Mass Spectrometry
pp. 1-4(4)
Authors: Hsieh, Yunsheng; Chen, Jiwen; Knemeyer, Ian; Crossman, Lee; Korfmacher, Walter A.

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Phenotyping of Cytochrome P450 3A Enzyme in Gujarat Population
pp. 5-10(6)
Authors: Jani, Ashutosh J.; Rathnam, Shivprakash; Mehta, Anita A.

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Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats
pp. 11-17(7)
Authors: Manautou, Jose E.; Nowicki, Michael T.; Aleksunes, Lauren M.; Sawant, Sharmilee P.; Dnyanmote, Ankur V.; Mehendale, Harihara M.

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Allelic Variations in 5, 10-Methylenetetrahydrofolate Reductase Gene and Susceptibility to Cervical Cancer in Indian Women
pp. 18-22(5)
Authors: Naqvi, Samar H.; Nandan, Naveen Kumar; Wajid, Saima; Biswas, Shilpie; Juneja, Sominder Singh; Rizvi, Moshahid; Prakash, Raminder

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Modulation of Porcine (Sus scrofa domestica) and Pheasant (Phasianus colchicus) Carbonyl Reducing Enzymes by Anthelmintic Therapy with Flubendazole
pp. 29-34(6)
Authors: Szotakova, Barbora; Nobilis, Milan; Lamka, Jiri; Krizova, Veronika; Savlik, Michal; Skalova, Lenka

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Identification of a Novel Glutathione Conjugate of Diclofenac by LTQOrbitrap
pp. 35-40(6)
Authors: Teffera, Yohannes; Waldon, Daniel J.; Colletti, Adria E.; Albrecht, Brian K.; Zhao, Zhiyang

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Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes
pp. 60-66(7)
Authors: Zhou, Shu-Feng; Deng, Ying; Bi, Hui-chang; Zhao, Li-zi; Wang, Xue-ding; Chen, Jie; Ou, Zhi-min; Ding, Liang; Xu, Le-jia; Guan, Su; Chen, Xiao; Huang, Min

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Free Content Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes
pp. 67-75(9)
Authors: Kneip, Christa; Terlinden, Rolf; Beier, Horst; Chen, Genfu

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