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Drug Metabolism Letters publishes short papers on major advances in all areas of drug metabolism and disposition. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of the Internet technology for both the submission and review of manuscripts. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates.

Publisher: Bentham Science Publishers

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Volume 1, Number 4, 2007

Articles

Inhibition of Calcium Oxalate Nephrotoxicity with Cymbopogon Schoenanthus (Al-Ethkher)
pp. 241-244(4)
Authors: Al-Ghamdi, Saeed S.; Al-Ghamdi, Abdullah A.; Shammah, Ahmed A.

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Modelling and Measuring Redox Cycling and Cytotoxicity of Quinones
pp. 245-253(9)
Authors: Hughes, Louise; Wingate, Jordana; Griffith, Renate; Aitken, R. J.

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Endothelial Cell-Based Methods for the Detection of Cyanobacterial Anti- Inflammatory and Wound-Healing Promoting Metabolites
pp. 254-260(7)
Authors: Wiesner, Christoph; Kopecky, Jiri; Pflueger, Maren; Hundsberger, Harald; Entler, Barbara; Kleber, Christoph; Atzler, Josef; Hrouzek, Pavel; Stys, Dalibor; Lukesova, Alena; Schuett, Wolfgang; Lucas, Rudolf

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Clinically Significant Proteinuria Following the Administration of Sirolimus to Renal Transplant Recipients
pp. 267-271(5)
Authors: Perlman, Alan S.; Kim, Eugene H.; Kallakury, Bhaskar; Light, Jimmy A.; Moore, Jr., Jack

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Metabolite Interference in Pharmacokinetic Studies
pp. 272-275(4)
Authors: Moghaddam, Mehran F.; Fan, Jui-Hsiang; Tang, Yang; Khatsenko, Oleg; Katz, Jason C.; Shirley, Michael A.

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Allelic Variations in CYP2D6 Gene and Susceptibility to Cervical Cancer
pp. 276-280(5)
Authors: Wajid, S.; Naqvi, S. H.; Juneja, A.; Bharadwaj, M.; Mitra, A. B.

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Comprehensive Identification of Cytochrome P450 Isoforms from Solubility-Based Fractionated Rat Liver Microsomes
pp. 281-286(6)
Authors: Yamanaka, Hidenori; Takeyoshi, Masahiro; Minobe, Yasushi; Yakabe, Yoshikuni; Takatsuki, Mineo; Sato, Hisaya

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LC-MS/MS-Based Approach for Obtaining Exposure Estimates of Metabolites in Early Clinical Trials Using Radioactive Metabolites as Reference Standards
pp. 293-298(6)
Authors: Zhang, Donglu; Raghavan, Nirmala; Chando, Theodore; Gambardella, Janice; Fu, Yunlin; Zhang, Duxi; Unger, Steve E.; Humphreys, W. G.

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In Vitro Metabolism of Leflunomide by Mouse and Human Liver Microsomes
pp. 299-305(7)
Authors: Chan, Eric C.Y.; New, Lee-Sun

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A New Method to Measure P-gp (ABCB1) Activity
pp. 306-310(5)
Authors: Masuda, Masatoshi; Mizutani, Takaharu

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Glucocorticoid Receptor Functions in HeLa Cells Are Perturbed by 2,3,8,9-tetrachlorodibenzo-p-dioxin (TCDD)
pp. 311-314(4)
Authors: Vrzal, Radim; Ulrichova, Jitka; Dvorak, Zdenek; Pavek, Petr

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