Skip to main content
padlock icon - secure page this page is secure

Plants and Phytocompounds Active Against Bothrops Venoms

Buy Article:

$68.00 + tax (Refund Policy)

Snakebite envenomation is an important health problem in tropical countries, with severe human and social consequences. In Latin America, the Bothrops species constitute the main threat to humans, and the envenomation caused by these species quickly develops into severe local tissue damage, including swelling, hemorrhaging, myonecrosis, skin ulceration, and pain. The systemic effects of envenomation are usually neutralized by antivenom serum therapy, despite its intrinsic risks. However, neutralization of local tissue damage remains a challenge. To improve actual therapy, two major alternatives are proposed: the rational design of new specific antibodies for most of the tissue damaging/ poor immunogenic toxins, or the search for new synthetic or natural compounds which are able to inhibit these toxins and complement the serum therapy. Natural compounds isolated from plants, mainly from those used in folk medicine to treat snakebite, are a good choice for finding new lead compounds to improve snakebite treatment and minimize its consequences for the victims. In this article, we reviewed the most promising plants and phytocompounds active against bothropic venoms.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Anti-bothropic serum; Bothrops; Medicinal plants; Natural inhibitors; Secondary metabolites; Snakebite envenomation

Document Type: Review Article

Publication date: September 1, 2019

This article was made available online on September 26, 2019 as a Fast Track article with title: "Plants and Phytocompounds Active Against Bothrops Venoms".

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more