Current Topics in Medicinal Chemistry

Graphical Abstracts
pp. i-iv(4)

Editorial: Drug Discovery for Neglected Diseases
pp. 313-314(2)
Authors: Andricopulo, Adriano D.; Ferreira, Leonardo L.G.

Ubiquitin Proteasome System as a Potential Drug Target for Malaria
pp. 315-320(6)
Authors: Pereira, Pedro H. Scarpelli; Curra, Chiara; Garcia, Celia R.S.

Polyamines and Related Nitrogen Compounds in the Chemotherapy of Neglected Diseases Caused by Kinetoplastids
pp. 321-368(48)
Authors: Bisceglia, Juan A.; Mollo, Maria C.; Gruber, Nadia; Orelli, Liliana R.

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases
pp. 369-381(13)
Authors: Bellera, Carolina L.; Sbaraglini, Maria L.; Talevi, Alan

Insights into Anti-Trypanosomal Agents Based on Synthetic Glycoconjugates
pp. 382-396(15)
Authors: Campo, Vanessa L.; Marchiori, Marcelo Fiori; Carvalho, Ivone

Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma brucei Aldolase Inhibitors
pp. 397-405(9)
Authors: Ferreira, Leonardo L.G.; Ferreira, Rafaela S.; Palomino, David L.; Andricopulo, Adriano D.

Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification
pp. 406-417(12)
Authors: Teles, Andre L. B.; Silva, Roseane R.; Ko, Michelle; Ferreira, Glaucio M.; Pita, Samuel da Rocha; Trossini, Gustavo Henrique Goulart; Carvalho, Paulo; Castilho, Marcelo Santos

First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties
pp. 418-427(10)
Authors: Carballeira, Nestor M.; Morales-Guzman, Christian; Alvarez-Benedicto, Ester; Torres-Martinez, Zally; Delgado, Yamixa; Griebenow, Kai H.; Tinoco, Arthur D.; Reguera, Rosa M.; Perez-Pertejo, Yolanda; Carbajo-Andres, Ruben; Balana-Fouce, Rafael