Current Topics in Medicinal Chemistry

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Editorial (Thematic Issue: Drug Reprofiling: An Alternative Path to Drug Discovery)
pp. 2067-2068(2)
Author: S. Ramaa, C.

Computational Drug Repositioning: A Lateral Approach to Traditional Drug Discovery?
pp. 2069-2077(9)
Authors: U. Sahu, Niteshkumar; S. Kharkar, Prashant

The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough
pp. 2078-2087(10)
Author: Talevi, Alan

The Repurposing of Old Drugs or Unsuccessful Lead Compounds by in Silico Approaches: New Advances and Perspectives
pp. 2088-2106(19)
Authors: Martorana, Annamaria; Perricone, Ugo; Lauria, Antonino

Scaffold Repurposing of Old Drugs Towards New Cancer Drug Discovery
pp. 2107-2114(8)
Authors: Chen, Haijun; Wu, Jianlei; Gao, Yu; Chen, Haiying; Zhou, Jia

Reprofiling of Troglitazone Towards More Active and Less Toxic Derivatives: A New Hope for Cancer Treatment?
pp. 2115-2124(10)
Authors: Mazerbourg, Sabine; Kuntz, Sandra; Grillier-Vuissoz, Isabelle; Berthe, Audrey; Geoffroy, Marine; Flament, Stéphane; Bordessa, Andrea; Boisbrun, Michel

Repositioning of DHFR Inhibitors
pp. 2125-2143(19)
Authors: Chandrashekhar Lele, Arundhati; Amarnath Mishra, Deepak; Karmila Kamil, Tengku; Bhakta, Sanjib; Sohel Degani, Mariam

Revisiting Non-Cancer Drugs for Cancer Therapy
pp. 2144-2155(12)
Authors: Ju Yang, Eun; Wu, Changjie; Liu, Yifan; Lv, Junfang; Sup Shim, Joong

An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs
pp. 2156-2168(13)
Authors: Bhattarai, Deepak; Singh, Sarbijt; Jang, Yerin; Hyeon Han, Seung; Lee, Kyeong; Choi, Yongseok

Repurposing Drugs for Cancer Prevention
pp. 2169-2178(10)
Authors: K. Lee, Daniel; Szabo, Eva

Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment
pp. 2179-2188(10)
Authors: C. Zheng, Yi; Yu, Bin; Z. Jiang, Guo; J. Feng, Xue; X. He, Peng; Y. Chu, Xiao; Zhao, Wen; M. Liu, Hong

Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario
pp. 2189-2200(12)
Authors: B. Katare, Parmeshwar; K. Banerjee, Sanjay

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option
pp. 2201-2222(22)
Authors: Laura Sbaraglini, María; Cristina Vanrell, María; Leticia Bellera, Carolina; Benaim, Gustavo; Carrillo, Carolina; Talevi, Alan; Silvia Romano, Patricia

Metformin - The Drug for the Treatment of Autoimmune Diseases; A New Use of a Known Anti-Diabetic Drug
pp. 2223-2230(8)
Authors: Tomczynska, Malgorzata; Bijak, Michal; Saluk, Joanna