Current Topics in Medicinal Chemistry

Graphical Abstracts:
pp. i-iii(3)

Editorial (Thematic Issue: Drug Design and Discovery Targeting Ion Channels)
pp. 1763-1763(1)
Author: Li, Xin

HCN Channels Modulators: The Need for Selectivity
pp. 1764-1791(28)
Authors: Novella Romanelli, Maria; Sartiani, Laura; Masi, Alessio; Mannaioni, Guido; Manetti, Dina; Mugelli, Alessandro; Cerbai, Elisabetta

Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation
pp. 1792-1818(27)
Authors: A. Pearlstein, Robert; Andrew MacCannell, K.; Erdemli, Gül; Yeola, Sarita; Helmlinger, Gabriel; Hu, Qi-Ying; Farid, Ramy; Egan, William; Whitebread, Steven; Springer, Clayton; Beck, Jeremy; Wang, Hao-Ran; Maciejewski, Mateusz; Urban, Laszlo; S. Duca, José

Computer-Aided Drug Discovery and Design Targeting Ion Channels
pp. 1819-1829(11)
Authors: Zhang, Qiansen; Gao, Zhaobing; Yang, Huaiyu

Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors
pp. 1830-1842(13)
Authors: Kassenbrock, Alina; Vasdev, Neil; H. Liang, Steven

Kv1.5 Inhibitors for Treatment of Atrial Fibrillation: A Tradeoff between Selectivity and Non-selectivity
pp. 1843-1854(12)
Authors: Guo, Xiaoke; Chen, Weilin; Sun, Haopeng; You, Qidong

HCN Channel as Therapeutic Targets for Heart Failure and Pain
pp. 1855-1861(7)
Authors: Cao, Ying; Pang, Jianxin; Zhou, Pingzheng

Studies on Chloride Channels and their Modulators
pp. 1862-1876(15)
Authors: M. Patil, Vaishali; P. Gupta, Satya

Progress in Research of KV1.1 and KV1.3 Channels as Therapeutic Targets
pp. 1877-1885(9)
Authors: Zhao, Wei; Chen, Yuan