Current Topics in Medicinal Chemistry

Editorial [Hot topic: Applying Induced Fit in Drug Discovery: Square Pegs and Round Holes? (Guest Editors: Francesca Spyrakis, Pietro Cozzini, Aurijit Sarkar and Glen E. Kellogg)]
pp. 131-132(2)
Authors: Spyrakis, Francesca; Cozzini, Pietro; Sarkar, Aurijit; E. Kellogg, Glen

Induced Fit Simulations on Nuclear Receptors
pp. 133-147(15)
Authors: Nocker, Monika; Cozzini, Pietro

Biochemical and Structural Investigations on Kynurenine Aminotransferase II: An Example of Conformation-Driven Species-Specific Inhibition?
pp. 148-157(10)
Authors: Casazza, Valentina; Rossi, Franca; Rizzi, Menico

Ligands Turning Around in the Midst of Protein Conformers: The Origin of Ligand-Protein Mating. A NMR View
pp. 158-170(13)
Authors: A. Pertinhez, T.; Spisni, A.

Accommodating Protein Flexibility for Structure-Based Drug Design
pp. 171-178(8)
Author: Lin, Jung-Hsin

Accounting for Induced-Fit Effects in Docking: What is Possible and What is Not?
pp. 179-191(13)
Author: A. Sotriffer, Christoph

Protein Flexibility and Ligand Recognition: Challenges for Molecular Modeling
pp. 192-210(19)
Authors: Spyrakis, Francesca; BidonChanal, Axel; Barril, Xavier; Javier Luque, F.

Thermal Motions of the E. coli Glucose-Galactose Binding Protein Studied Using Well-Sampled Semi-Atomistic Simulations
pp. 211-220(10)
Authors: J. Cashman, D.; B. Mamonov, A.; Bhatt, D.; M. Zuckerman, D.

Melatonin-mitochondria Interplay in Health and Disease
pp. 221-240(20)
Authors: Acuna Castroviejo, Dario; C. Lopez, Luis; Escames, Germaine; Lopez, Ana; A. Garcia, Jose; J. Reiter, Russel

A Closer Look at the High Affinity Benzodiazepine Binding Site on GABAA Receptors
pp. 241-246(6)
Authors: Sigel, Erwin; P. Luscher, Benjamin