Current Topics in Medicinal Chemistry

Editorial [ Hot Topic : Receptor Dimerization and Bivalent Ligands, an Emerging Topic for Drug Design (Guest Editor: Dr. Ao Zhang) ]
pp. 341-341(1)
Authors: Zhang, Ao; Neumeyer, John L.

Receptor Dimerization - Rationale for the Design of Bivalent Ligands
pp. 343-345(3)
Authors: Zhang, Ao; Liu, Zhili; Kan, Ying

Agonistic and Antagonistic Bivalent Ligands for Serotonin and Dopamine Receptors Including their Transporters
pp. 347-353(7)
Authors: Decker, Michael; Lehmann, Jochen

Probing the Membrane Targeting C1 Subdomains of PKC with Bivalent Ligands
pp. 355-362(8)
Author: Nowak, Ireneusz

Kappa Receptor Bivalent Ligands
pp. 363-373(11)
Authors: Peng, Xuemei; Neumeyer, John L.

Bivalent Ligands Derived from Huperzine A as Acetylcholinesterase Inhibitors
pp. 375-387(13)
Authors: Haviv, H.; Wong, D. M.; Silman, I.; Sussman, J. L.

Editorial [ Hot Topic : Viagra's Cousins - Towards a New Generation of Phosphodiesterase Inhibitors (Guest Editor: Philip Thompson) ]
pp. 389-389(1)
Author: Thompson, Philip

Crystal Structures of Phosphodiesterases and Implications on Substrate Specificity and Inhibitor Selectivity
pp. 391-403(13)
Authors: Ke, Hengming; Wang, Huanchen

Design of Second Generation Phosphodiesterase 5 Inhibitors
pp. 405-419(15)
Authors: Palmer, Michael J.; Bell, Andrew S.; Fox, David N. A.; Brown, David G.

Re-Discovering PDE3 Inhibitors - New Opportunities for a Long Neglected Target
pp. 421-436(16)
Authors: Thompson, Philip E.; Manganiello, Vincent; Degerman, Eva

The Novel Functions of cGMP-Specific Phosphodiesterase 5 and its Inhibitors in Carcinoma Cells and Pulmonary/Cardiovascular Vessels
pp. 437-454(18)
Authors: Zhu, Bing; Strada, Samuel J

Corrigendum
pp. 455-455(1)