Current Topics in Medicinal Chemistry

Editorial [Hot Topic: p38 Kinase Inhibitor (Guest Editor: Katerina Leftheris)]
pp. 919-919(1)
Author: Leftheris, Katerina

The Biology of p38 Kinase: A Central Role in Inflammation
pp. 921-928(8)
Author: Schieven, Gary L.

Potential Adverse Effects Associated with Inhibition of p38α/β MAP Kinases
pp. 929-939(11)
Author: Dambach, Donna M.

Discovery of Highly Selective Inhibitors of p38α
pp. 941-951(11)
Authors: Popa-Burke, Ioana; Birkos, Steve; Blackwell, Leonard; Cheatham, Lynn; Clark, Jennifer; Dickson, Jr., John K.; Galasinski, Scott; Janzen, William P.; Mendoza, Jose; Miller, Jennifer L.; Mohney, Robert P.; Steed, Paul M.; Hodge, C. N.

The Discovery of Novel Chemotypes of p38 Kinase Inhibitors
pp. 953-965(13)
Authors: Diller, David J.; Lin, Tsung H.; Metzger, Axel

Small Molecule p38 Inhibitors: Novel Structural Features and Advances from 2002-2005
pp. 967-985(19)
Authors: Hynes, Jr., John; Leftheris, Katerina

P38 MAP Kinase Inhibitors: Evolution of Imidazole-Based and Pyrido- Pyrimidin-2-One Lead Classes
pp. 987-1003(17)
Authors: Natarajan, Swaminathan R.; Doherty, James B.

Structural Comparison of p38 Inhibitor-Protein Complexes: A Review of Recent p38 Inhibitors Having Unique Binding Interactions
pp. 1005-1016(12)
Authors: Wrobleski, Stephen T.; Doweyko, Arthur M.

Pathway to the Clinic: Inhibition of P38 MAP Kinase. A Review of Ten Chemotypes Selected for Development
pp. 1017-1029(13)
Authors: Goldstein, David M.; Gabriel, Tobias