Current Topics in Medicinal Chemistry

Preface [Hot topic: Modern Aspects in the Design And Discovery of Novel Antihypertensive Drugs (Guest Editor: Thomas Mavromoustakos)]
pp. i-i(1)
Author: Mavromoustakos, Thomas

Conformation and Bioactivity. Design and Discovery of Novel Antihypertensive Drugs
pp. 385-401(17)
Authors: Mavromoustakos, T.; Zervou, M.; Zoumpoulakis, P.; Kyrikou, I.; Benetis, N. P.; Polevaya, L.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P. M.

Structural Features of Angiotensin-I Converting Enzyme Catalytic Sites: Conformational Studies in Solution, Homology Models and Comparison with Other Zinc Metallopeptidases
pp. 403-429(27)
Authors: Spyroulias, Georgios A.; Galanis, Athanassios S.; Pairas, George; Manessi-Zoupa, Evy; Cordopatis, Paul

On the Structural Basis of the Hypertensive Properties of Angiotensin II: A Solved Mystery or a Controversial Issue?
pp. 431-444(14)
Authors: Tzakos, Andreas G.; Gerothanassis, Ioannis P.; Troganis, Anastassios N.

Efforts to Understand the Molecular Basis of Hypertension Through Drug:Membrane Interactions
pp. 445-459(15)
Authors: Mavromoustakos, T.; Zoumpoulakis, P.; Kyrikou, I.; Zoga, A.; Siapi, E.; Zervou, M.; Daliani, I.; Dimitriou, D.; Pitsas, A.; Kamoutsis, C.; Laggner, P.

Simulating Physiology and Methods for Therapeutic Evaluation with Emphasis on Hypertension
pp. 461-471(11)
Authors: Macpherson, A. K.; Neti, S.

Renin-angiotensin System Blockade at the Level of the Angiotensin Converting Enzyme or the Angiotensin Type-1 Receptor: Similarities and Differences
pp. 473-481(9)
Authors: Stergiou, George S.; Skeva, Irini I.

Hematocrit-lowering Effect Following Inactivation of Renin-Angiotensin System with Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers
pp. 483-486(4)
Authors: Marathias, K. P.; Agroyannis, B.; Mavromoustakos, T.; Matsoukas, J.; Vlahakos, D. V.

The Shift in the “Paradigm” of the Pharmacology of Hypertension
pp. 487-498(12)
Authors: Flordellis, Christodoulos S.; Goumenos, Dimitrios; Kourounis, George; Tsementzis, Sotirios A.; Paris, Herve; Vlachojiannis, Jaannis