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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 7, Number 1, January 2012

Articles

Open Access Preface
pp. 1-1(1)
Authors: Keri, Gyorgy; Ullrich, Axel

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Open Access Targeting the Epidermal Growth Factor Receptor in Glioblastoma Treatment
pp. 3-13(11)
Authors: Merkur, N.; Westhoff, M.-A.; Karpel-Massler, G.; Halatsch, M.-E.

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Open Access Astrocyte Signaling and Multiple Sclerosis
pp. 14-19(6)
Authors: D'haeseleer, Miguel; Cambron, Melissa; De Keyser, Jacques

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Open Access Signal Transduction in HIV Protein-Treated Astrocytes
pp. 28-34(7)
Authors: Yao, Honghong; Bethel-Brown, Crystal; Yang, Lu; Cai, Yu; Kanmogne, Marlene; Mudgapalli, Vikas; Fields, Natasha; Buch, Shilpa

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Open Access Emerging Role of NF-κB in the Pathogenesis of Hepatic Encephalopathy
pp. 35-42(8)
Authors: Jayakumar, A.R.; Norenberg, M.D.

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Open Access Adrenergic and V1-ergic Agonists/Antagonists Affecting Recovery from Brain Trauma in the Lund Project Act on Astrocytes
pp. 43-55(13)
Authors: Peng, Liang; Du, Ting; Xu, Junnan; Song, Dan; Li, Baoman; Zhang, Meixia; Hertz, Leif

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Open Access Astrocytic Signaling in Persistent Pain
pp. 56-74(19)
Authors: Chu, Yu-Xia; Zhao, Zhi-Qi; Wei, Feng

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Open Access Astrocytes as a 5-HT2B-Mediated SERT-Independent SSRI Target, Slowly Altering Depression-Associated Genes and Function
pp. 65-80(16)
Authors: Hertz, Leif; Li, Baoman; Song, Dan; Ren, Jienan; Dong, Lu; Chen, Ye; Peng, Liang

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Open Access Role of Fibroblast Growth Factor Receptors in Astrocytic Stem Cells
pp. 81-86(6)
Authors: Y. Galvez-Contreras, Alma; E. Gonzalez-Castaneda, Rocio; Luquin, Sonia; Gonzalez-Perez, Oscar

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