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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 3, Number 2, May 2008

Articles

The Role of Parthenolide in Intracellular Signalling Processes: Review of Current Knowledge
pp. 82-87(6)
Authors: Bedoya, Luis M.; Abad, Maria Jose; Bermejo, Paulina

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Intracellular Signaling Triggered by Formyl-Peptide Receptors in Nonphagocytic Cells
pp. 88-96(9)
Authors: Iaccio, Annalisa; Angiolillo, Antonella; Ammendola, Rosario

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Novel Therapeutic Targets for the Treatment of Tubulointerstitial Fibrosis
pp. 97-111(15)
Authors: Prakash, Jai; Poelstra, Klaas; Goor, Harry v.; Moolenaar, Frits; Meijer, Dirk K.F.; Kok, Robbert J.

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Signal Transduction Targets in Prostate Cancer
pp. 112-128(17)
Authors: Koul, Hari K.; Khandrika, Lakshmipathi

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Pathogen-Related Signal Transduction Pathways of Dendritic Cells: Perspectives for Cancer Immunotherapy
pp. 133-137(5)
Authors: Kato, Tomonori; Ueda, Yasuji; Kinoh, Hiroaki; Tsukada, Kaori; Ichikawa, Tomohiko; Yonemitsu, Yoshikazu

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Regulation of the PI3K-Akt Network: Current Status and a Promise for the Treatment of Human Diseases
pp. 138-151(14)
Authors: Noguchi, Masayuki; Obata, Toshiyuki; Suizu, Futoshi

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