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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 2, Number 2, May 2007

Articles

Targeting Neurotrophic Signal Transduction Pathways in the Treatment of Mood Disorders
pp. 101-110(10)
Authors: Gould, Todd D.; Manji, Husseini K.

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Smad-Signaling in Mammary Gland Development and Tumorigenesis
pp. 111-120(10)
Authors: Gupta, Vandana; Thiagalingam, Arunthathi; Maheswaran, Shyamala

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Nitric Oxide: Friendly Rivalry in Tuberculosis
pp. 121-128(8)
Authors: Mukhopadhyay, Sangita; Nair, Shiny; Hasnain, Seyed E.

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Potential Utilization of Bystander / Abscopal-Mediated Signal Transduction Events in the Treatment of Solid Tumors
pp. 129-143(15)
Authors: Peters, Matthew E.; Shareef, Mohammed M.; Gupta, Seema; Zagurovskaya-Sultanov, Marianna; Kadhim, Munira; Mohiuddin, Mohammed; Ahmed, Mansoor M.

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Oncogene-Directed Therapies as Modulators of Cancer Coagulopathy, Angiogenesis and Tumor-Vascular Interface
pp. 157-163(7)
Authors: Rak, Janusz; Milsom, Chloe; May, Linda; Yu, Joanne

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Molecular Rationales for Signal Transduction Therapy and Chemoprevention of BRCA1-Related Breast and Ovarian Tumours
pp. 165-173(9)
Authors: Tagliaferri, P.; Tassone, P.; Pietragalla, A.; Rotundo, M. S.; Barbieri, V.; Budillon, A.; Caraglia, M.; Costanzo, F. S.; Venuta, S.

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Blocking Apoptotic Intracellular Signaling Cascades with Cell-Permeable Peptides
pp. 175-179(5)
Authors: Zine, Azel; Uziel, Alain; Beckmann, Jacques; Bonny, Christophe

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