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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 2, Number 1, January 2007

Addendum

Author Index To Volume 1
pp. i-ii(2)
Author: Publishers

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Subject Index Volume 1
pp. iii-vii(5)
Author: Publishers

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Articles

Signal Transduction Therapy: Challenges to Clinical Trial Design
pp. 21-30(10)
Authors: Hussain, Syed A.; Rea, Daniel W.; James, Nicholas D.; Palmer, Daniel H.

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IL-13 and its Signal Pathway: Promising Targets in the Development of a Therapeutic Agent for Bronchial Asthma
pp. 31-40(10)
Authors: Izuhara, Kenji; Arima, Kazuhiko; Kanaji, Sachiko; Kanaji, Taisuke; Ohta, Shoichiro

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Cellular Signaling in Cartilage Tissue Engineering
pp. 41-48(8)
Author: Lammi, Mikko J.

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The Role of Connexins in Carcinogenesis: Review of Current Knowledge
pp. 49-56(8)
Authors: Luiza, Kanczuga-koda; Stanislaw, Sulkowski; Mariusz, Koda; Andrzej, Wincewicz; Tadeusz, Rutkowski; Mariola, Moniuszko

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Signal Transduction Therapy of Diabetic Vascular Complication
pp. 91-100(10)
Authors: Yamagishi, Sho-ichi; Nakamura, Kazuo; Matsui, Takanori; Yoshida, Yumiko; Takenaka, Katsuhiko; Jinnouchi, Yuko; Imaizumi, Tsutomu

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