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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 1, Number 3, 2006

Articles

STAT3: A Molecular Target for Cancer Whose Time Has Come
pp. 239-253(15)
Author: Barton, Beverly E.

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n-3 Polyunsaturated Fatty Acids as Signal Transduction Modulators and Therapeutical Agents in Cancer
pp. 255-271(17)
Authors: Calviello, Gabriella; Serini, Simona; Palozza, Paola

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Emerging Role of Stromal Fibroblasts in Epithelial Cancer
pp. 273-283(11)
Authors: Rita Rippo, Maria; Procopio, Antonio; Catalano, Alfonso

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Targeting Prenylated RAS Modifying Enzymes in Cancer Cells
pp. 285-293(9)
Author: Chen, Yulong L.

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Targeting Phospholipase D-mediated Survival Signals in Cancer
pp. 295-303(9)
Author: Foster, David A.

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The Role of Heat Shock Protein 90 and Endothelial Nitric Oxide Synthase Signaling in Cardiovascular Therapy
pp. 305-315(11)
Authors: Presley, Tennille; Kuppusamy, Periannan; Zweier, Jay L.; Ilangovan, Govindasamy

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PDX-1 and MafA as Potential Therapeutic Targets for Diabetes
pp. 317-324(8)
Authors: Kaneto, Hideaki; Miyatsuka, Takeshi; Matsuoka, Taka-aki

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Carotenoids as Modulators of Intracellular Signaling Pathways
pp. 325-335(11)
Authors: Palozza, Paola; Serini, Simona; Calviello, Gabriella

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