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In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.

The aim of this journal is to publish timely in-depth reviews as well as original papers in the field of signal transduction therapy. Thematic issues will also be published to cover selected areas of signal transduction therapy. Coverage of the field will include genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases.

Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 1, Number 2, May 2006

Articles

Life and Death of Nerve Cells: Therapeutic Cytokine Signaling Pathways
pp. 133-146(14)
Authors: Eisel, Ulrich L.M.; Biber, Knut; Luiten, Paul G.M.

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Involvement of Targeting and Scaffolding Proteins in the Regulation of the EGFR/Ras/MAPK Pathway in Oncogenesis
pp. 147-167(21)
Authors: Grewal, Thomas; Tebar, Francesc; Pol, Albert; Enrich, Carlos

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Signal Transduction Therapy Targeting Apoptosis Pathways in Cancers
pp. 179-190(12)
Authors: Fulda, Simone; Debatin, Klaus-Michael

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T-Cell Zeta Chain Expression, Phosphorylation and Degradation and their Role in T-Cell Signal Transduction and Immune Response Regulation in Health And Disease
pp. 191-208(18)
Authors: Eleftheriadis, Theodoros; Antoniadi, Georgia; Liakopoulos, Vassilios; Kortsaris, Alexandros

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Erythropoietin Signaling and Neuroprotection
pp. 209-218(10)
Authors: Genc, Sermin; Egrilmez, Mehtap Y.; Genc, Kursad

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Integrin-Mediated Drug Resistance
pp. 227-237(11)
Authors: Ambriovic-Ristov, Andreja; Osmak, Maja

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