Skip to main content
padlock icon - secure page this page is secure

Free Content Cough and Asthma

Download Article:
 Download
(PDF 353.4 kb)
 
Cough is the most common complaint for which patients seek medical attention. Cough variant asthma (CVA) is a form of asthma, which presents solely with cough. CVA is one of the most common causes of chronic cough. More importantly, 30 to 40% of adult patients with CVA, unless adequately treated, may progress to classic asthma. CVA shares a number of pathophysiological features with classic asthma such as atopy, airway hyper-responsiveness, eosinophilic airway inflammation and various features of airway remodeling. Inhaled corticosteroids remain the most important form of treatment of CVA as they improve cough and reduce the risk of progression to classic asthma most likely through their prevention of airway remodeling and chronic airflow obstruction.





No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Chronic cough; ELISA method; IgE; Mast cells; Sinobronchial syndrome (SBS); Sputum mucin; aeroallergens; airway hyper-responsiveness; airway inflammation; asthma; atopic cough; beta-agonists; biopsy; bronchial mucosal tissue; bronchoalveolar lavage (BAL); bronchoconstriction; bronchodilator-resistant dry cough; bronchodilators; capsaicin; chronic airflow obstruction; classic asthma (CA); computed tomography (CT); cough variant asthma; cough-predominant asthma; cough-reflux selfperpetuating positive feedback cycle; dyspnea; eosinophilic tracheobronchitis; eosinophils; fibrogenic mediators; goblet cell; goblet cell hyperplasia; histamine; histamine H1 receptor antagonists; hyperplasia; inhaled corticosteroid; leukocytes; leukotriene receptor antagonists; leukotrienes C4, D4 and E4; lung parenchyma; methacholine; neutrophilic inflammation; non-asthmatic eosinophilic bronchitis (NAEB); peak expiratory flow (PEF); productive cough; prostaglandins D2; skin test; sputum eosinophilia; theophyllines; thromboxane synthesis inhibitors; vascular proliferation

Document Type: Research Article

Publication date: February 1, 2011

More about this publication?
  • Current Respiratory Medicine Reviews publishes frontier reviews on all the latest advances on respiratory diseases and its related areas e.g. pharmacology, pathogenesis, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in respiratory medicine.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more