Alternative Methodologies for Halogenation of Organic Compounds
It is difficult to imagine organic chemistry without organo-halogen compounds and the molecular halogens needed for their preparation. In fact, It is implied that halogenation of organic compounds is a key industrial process; for example, the halogenated products are used in the synthesis of many pesticides and pharmaceuticals. Conventional halogenation methods typically use pollutant, toxic and corrosive elemental halogens (X2), which also generate hydrohalic acid as byproduct and effectively reduce the atom efficiency. Hence, to avoid their use, various modified reagents (N-halo reagents such as trichloisocyanuric acid, haloglycolurils, N-halosuccinimid and …), methods such as oxidative halogenation in the presence of alkali halogen salts, biohalogenations, solid phase and ionic liquid have been developed. In this review article, we will focus on strategies that are much greener and more sustainable than those using elemental halogens.
No Supplementary Data
No Article Media
Document Type: Research Article
Publication date: December 1, 2013
More about this publication?
- Current Organic Synthesis publishes in-depth reviews on all areas of synthetic organic chemistry i.e. asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions. The journal is essential reading to all synthetic organic chemists. Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.
- Editorial Board
- Information for Authors
- Subscribe to this Title
- Ingenta Connect is not responsible for the content or availability of external websites