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Free Content Domino/Cascade and Multicomponent Reactions for the Synthesis of Thiazole Derivatives

Substituted thiazoles are widely known as natural products, approved drugs, and a number of synthetic compounds as bioactive agents. Due to the worth of this heterocycle nucleus, a large number of synthetic methodologies have been reported over the years to synthesize its derivatives. In this perspective, recent advances in the synthesis of thiazole compounds by using domino/cascade and multicomponent approaches have been summarized.

Keywords: Domino/cascade reaction; anticancer; fused-thiazole; isothiazole; multicomponent reaction; thiazole; thiazoline; thiazolo-androstenone

Document Type: Miscellaneous

Publication date: February 1, 2022

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