Catalytic Enantioselective Constructions of Trifluoromethylated Chiral Stereogenic Centers via the Conjugate Addition to CF3-Alkenes: Overview of Current Progress
Synthetic methods for the enantioselective constructions of trifluoromethylated stereogenic centers are described. In particular, this review focuses on recent examples of catalytic enantioselective transformations with trifluoromethyl alkenes. These reactions efficiently synthesized
chiral compounds with trifluoromethylated stereogenic centers.
Keywords: Diels-Alder reaction; Trifluoromethyl group; chiral catalyst; conjugate addition; enantioselective synthesis; trifluoromethyl alkenes
Document Type: Research Article
Publication date: August 1, 2015
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