Synthesis, Photophysical and Photobiological Study of Synergic Photosensitizer:Zinc-Phthalocyanine with Ca2+ Chelating Agent
A novel phthalocyanine derivative containing a Ca2+ chelating agent with structure similar to EDTA has been synthesized in 3 steps. The addition of a chelating agent to the phthalocyanine macrocycle make it a synergic compound useful for PDT.
Keywords: Calcium affinity; MTT Assay; Photoinactivation; ZnPcChel; fluorescence emission
Document Type: Research Article
Affiliations: Departamento de Quimica,FFCLRP, Universidade de Sao Paulo, Av. dos Bandeirantes, 3900, 14040-901, Ribeirao Preto, SP, Brasil.
Publication date: 01 May 2007
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