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Central Nervous System Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new central nervous system agents. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics in central nervous system medicinal chemistry.

Central Nervous System Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in central nervous system drug discovery.

Publisher: Bentham Science Publishers

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Volume 9, Number 3, 2009

Articles

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In Vitro and Ex Vivo Characterization of Sigma-1 and Sigma-2 Receptors: Agonists and Antagonists in Biological Assays
pp. 161-171(11)
Authors: Colabufo, Nicola A.; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto; Roperto, Sante; Roperto, Franco

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Selective Sigma-1 (sig1) Receptor Antagonists: Emerging Target for the Treatment of Neuropathic Pain
pp. 172-183(12)
Authors: Diaz, Jose L.; Zamanillo, Daniel; Corbera, Jordi; Baeyens, Jose Manuel; Maldonado, Rafael; Pericàs, Miquel Angel; Vela, Jose Miguel; Torrens, Antoni

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Sigma-1 Receptor Chaperones and Diseases
pp. 184-189(6)
Authors: Tsai, Shang-Yi; Hayashi, Teruo; Mori, Tomohisa; Su, Tsung-Ping

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Imaging of Sigma1 Receptors in the Human Brain Using PET and [11C]SA4503
pp. 190-196(7)
Authors: Toyohara, Jun; Sakata, Muneyuki; Ishiwata, Kiichi

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1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (sig1) and Sigma-2 (sig2) Receptor Ligands: A Review
pp. 205-219(15)
Authors: Berardi, Francesco; Abate, Carmen; Ferorelli, Savina; Colabufo, Nicola A.; Perrone, Roberto

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Structure-Affinity-Relationship Study of Bicyclic sig Receptor Ligands
pp. 220-229(10)
Authors: Holl, Ralph; Geiger, Christian; Nambo, Masakazu; Itami, Kenichiro; Schepmann, Dirk; Wunsch, Bernhard

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Development of Molecular Probes for Imaging Sigma-2 Receptors in Vitro and in Vivo
pp. 230-245(16)
Authors: Mach, Robert H.; Wheeler, Kenneth Theodore

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A Structure-Affinity and Comparative Molecular Field Analysis of Sigma-2 (sig2) Receptor Ligands
pp. 246-257(12)
Authors: Abate, Carmen; Mosier, Philip D.; Berardi, Francesco; Glennon, Richard A.

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