Environmental Enrichment Influences BDNF and NR1 Levels in the Hippocampus and Restores Cognitive Impairment in Chronic Cerebral Hypoperfused Rats
Keywords: 2-VO; ANOVA; Alzheimer's disease; Brain-derived neurotrophic factor; CA1 region; Dunnett's post-test; Hippocampus; IOD; LTP; Morris Water Maze; N-methyl-D-aspartate receptor; NE; NR1; NR2B; PBS; SE; chronic cerebral hypoperfusion; dementia; enriched environment; mRNA; non-spatial memory; protein expression; spatial memory; western blotting; β-actin bands
Document Type: Research Article
Publication date: 01 November 2010
- Current Neurovascular Research (CNR) provides a cross platform for the publication of scientifically rigorous research that addresses disease mechanisms of both neuronal and vascular origins in neuroscience. The journal serves as an international forum for the publication of novel and pioneering original work as well as timely neuroscience research reviews in the disciplines of cell developmental disorders, plasticity, and degeneration that bridge the gap between basic science research and clinical discovery. CNR emphasizes the elucidation of disease mechanisms, both cellular and molecular, which can impact the development of unique therapeutic strategies for neuronal and vascular disorders.