Topoisomerase I Poisons and Suppressors as Anticancer Drugs
Keywords: DNA Cleavage; DNA intercalators; DNA minor groove binders; Hoechst 33258; Topotecan TPT Hycamtin; anthracyclines; anticancer Drugs; antitumor agents; camptotecin derivatives topotecan; camptothecins; diospyrin; doxorubicin adriamycin; enzyme; epipodophyllotoxins; favonoids; human cancer; indolocarbazole derivatives; irinotecan; mappia foetida; natural products lapcone; streptomycetes; suppressors; topoisomerase I DNA complex; topoisomerase I poisons; topoisomerase I suppressors; topostin; vincaalcaloids; zophenanthridine alkaloids
Document Type: Review Article
Publication date: 01 January 2000
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.