Targeting DNA with Triplexes
Keywords: DNA helix; G rich oligonucleotides; Purine analogues; RNA triple helices; Tethered DNA binding agents; antigene agents; antiparallel triplexes; base stacking; cytosine protonation; intercalators; intermolecular DNA triple elices; methylphosphonates; modified DNA sugars; naphthylquinoline derivatives; phosphorothioates; pyrimidine analogues; self association; sequence recognition; spermine; tethered triplex binding ligands; triplexes
Document Type: Review Article
Publication date: 01 January 2000
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.