Skip to main content
padlock icon - secure page this page is secure

The p53 Pathway Encounters the MicroRNA World

Buy Article:

$68.00 + tax (Refund Policy)

The p53 protein is a transcription factor that regulates multiple cellular processes in human and other high eukaryotes including cell proliferation, differentiation, cell cycle, and metabolism. The central roles played by p53 in tumor development have drawn extensive studies on p53 activation and inactivation. The regulation of p53 and its pathway, as well as its transactivational targets is of prime importance in the understanding of tumorigenesis. Recently, microRNAs (miRNAs) have been reported to be directly transactivated by p53. Equally, p53 and components of its pathway have been shown to be targeted by miRNA thereby affecting p53 activities. In this review, we focus our discussion on the biological and pathological roles of miRNAs in the p53 pathway.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: MicroRNA; p53

Document Type: Research Article

Publication date: May 1, 2009

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more