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The TB Structural Genomics Consortium: Providing a Structural Foundation for Drug Discovery

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Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.
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Keywords: antigen 85 protein; mt6 protein; mycobacterium tuberculosis; structural genomics; tuberculosis

Document Type: Review Article

Publication date: 01 June 2002

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