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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 18, Number 12, 2017

Articles

Free Content Graphical Abstracts
pp. i-viii(8)

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Free Content Editorial: Brain Hemorrhages and Future Management
pp. 1315-1315(1)
Authors: Chen, Gang; Lackner, Peter; Solaroglu, Ihsan; H. Zhang, John

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Aligning Animal Models of Clinical Germinal Matrix Hemorrhage, From Basic Correlation to Therapeutic Approach
pp. 1316-1328(13)
Authors: Lekic, Tim; Klebe, Damon; Pichon, Pilar; Brankov, Katarina; Sultan, Sally; McBride, Devin; Casel, Darlene; Al-Bayati, Alhamza; Ding, Yan; Tang, Jiping; H. Zhang, John

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Early Hematoma Enlargement in Primary Intracerebral Hemorrhage
pp. 1345-1348(4)
Authors: Cao, Du; Li, Qi; Fu, Peichun; Zhang, John; Yang, Jun

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A Therapeutic Target of Cerebral Hemorrhagic Stroke: Matrix Metalloproteinase- 9
pp. 1358-1366(9)
Authors: Dang, Baoqi; Duan, Xiaochun; Wang, Zhong; He, Weichun; Chen, Gang

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The Double Roles of the Prostaglandin E2 EP2 Receptor in Intracerebral Hemorrhage
pp. 1377-1385(9)
Authors: Luo, Xu; Zhu, Qiquan; Zhang, Jie; Huang, Qin; Xie, Zongyi; Cheng, Yuan

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The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke
pp. 1386-1391(6)
Authors: Oztop-Cakmak, Ozgur; Solaroglu, Ihsan; Gursoy-Ozdemir, Yasemin

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Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases
pp. 1392-1398(7)
Authors: Ma, Junwei; Wang, Yibin; Wang, Zhong; Li, Haiying; Wang, Zhimin; Chen, Gang

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Intraventricular Recombinant Tissue Plasminogen Activator in Treatment of Aneurysmal Intraventricular Hemorrhage: A Meta-Analysis
pp. 1399-1407(9)
Authors: Shi, LiGen; Xu, Liang; Shi, LuFeng; Brandon, Dixon; Chen, Sheng; Zhang, JianMin

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Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release After Spontaneous Subarachnoid Hemorrhage
pp. 1408-1416(9)
Authors: Josef Schiefecker, Alois; Dietmann, Anelia; Beer, Ronny; Pfausler, Bettina; Lackner, Peter; Kofler, Mario; Fischer, Marlene; Broessner, Gregor; Sohm, Florian; Mulino, Miriam; Thomé, Claudius; Humpel, Christian; Schmutzhard, Erich; Helbok, Raimund

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Nosocomial Infections and Antimicrobial Treatment in Coiled Patients with Aneurysmal Subarachnoid Hemorrhage
pp. 1417-1423(7)
Authors: Lackner, Peter; Mueller, Christoph; Beer, Ronny; Broessner, Gregor; Fischer, Marlene; Helbok, Raimund; Schiefecker, Alois; Schmutzhard, Erich; Pfausler, Bettina

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Early Brain Injury or Vasospasm? An Overview of Common Mechanisms
pp. 1424-1429(6)
Authors: Topkoru, Basak; Egemen, Emrah; Solaroglu, Ihsan; H. Zhang, John

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Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review
pp. 1430-1440(11)
Authors: Fischer, Marlene; Schiefecker, Alois; Lackner, Peter; Frank, Florian; Helbok, Raimund; Beer, Ronny; Pfausler, Bettina; Schmutzhard, Erich; Broessner, Gregor

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Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation
pp. 1441-1459(19)
Authors: Mann Ho, Wing; Reis, Cesar; Akyol, Onat; Yilmaz Akyol, Gokce; Applegate II, Richard; Stier, Gary; Martin, Robert; H. Zhang, John

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Targeting Transient Receptor Potential Canonical Channels for Diseases of the Nervous System
pp. 1460-1465(6)
Authors: Wang, Yibin; Bu, Jiyuan; Shen, Haitao; Li, Haiying; Wang, Zhong; Chen, Gang

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