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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 17, Number 13, 2016

Articles

Free Content Graphical Abstracts:
pp. i-iv(4)

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pp. 1453-1453(1)
Author: S. Smyth, Susan

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Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions
pp. 1455-1470(16)
Authors: Majtan, Tomas; L. Pey, Angel; Ereño-Orbea, June; Alfonso Martínez-Cruz, Luis; P. Kraus, Jan

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Natural and Unnatural Compounds Rescue Folding Defects of Human Alanine: Glyoxylate Aminotransferase Leading to Primary Hyperoxaluria Type I
pp. 1482-1491(10)
Authors: Oppici, Elisa; Montioli, Riccardo; Dindo, Mirco; Cellini, Barbara

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Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors Against Conformational and Infectious Diseases
pp. 1492-1505(14)
Authors: Velazquez-Campoy, Adrián; Sancho, Javier; Abian, Olga; Vega, Sonia

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Natural Small Molecules as Stabilizers and Activators of Cancer-Associated NQO1 Polymorphisms
pp. 1506-1514(9)
Authors: L. Pey, Angel; F. Megarity, Clare; Medina-Carmona, Encarnación; J. Timson, David

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Open Access Pharmacological Chaperones that Protect Tetrahydrobiopterin Dependent Aromatic Amino Acid Hydroxylases Through Different Mechanisms
pp. 1515-1526(12)
Authors: Hole, Magnus; Jorge-Finnigan, Ana; Underhaug, Jarl; Teigen, Knut; Martinez, Aurora

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Therapeutic Approaches Using Riboflavin in Mitochondrial Energy Metabolism Disorders
pp. 1527-1534(8)
Authors: J. Henriques, Bárbara; G. Lucas, Tânia; M. Gomes, Cláudio

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Dysregulated Chemokine Signaling in Cystic Fibrosis Lung Disease: A Potential Therapeutic Target
pp. 1535-1544(10)
Authors: Guan, Xiaoqing; Hou, Yuning; Sun, Fei; Yang, Zhe; Li, Chunying

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Topical and Transdermal Delivery of Drug-Loaded Nano/ Microsystems with Application of Physical Enhancement Techniques
pp. 1545-1559(15)
Authors: Neves Borgheti-Cardoso, Lívia; æ#130;ngelo, Tamara; M. Gelfuso, Guilherme; F.V. Lopez, Renata; Gratieri, Taís

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Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review
pp. 1560-1576(17)
Authors: Xie, Yuanchao; Alicha Ogah, Comfort; Jiang, Xiangrui; Li, Jianfeng; Shen, Jingshan

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